I can empathise with you there. My company have been taken over recently by a large one and although we have escaped the initial round of redundancies, It is becoming apparent that we would have to move offices in order to survive.
I can't afford to do that as milage would be ridiculous both timewise and in my pocket and I am not willing to give up the supra. Even with a company car i would still loose out - high tax and still have to put in fuel.
You have a much sought after skill and have to be hard hearted. Much as you enjoy your place of work, you can see it ending. Get something lined up now - no work = no income= no mortage!! work is a priority, I would get something close to where you want to be,EDIT: possibly rent out your current property and rent something closer to where you want to work/the missus job - wait until the job settles down then get back onto the housing ladder. You are young still and its not the end of the world that deals have fallen through at such an early stage of life (listen to granny! ) you will have other opportunities for houses and mortgages. Prices are stagnant if not falling in some areas right now, so it may pay you to wait anyway.
You are in a sticky position but I hope it works out, good luck with it all